Where in the World Is Karen Walker?

S2 E2: Will (Eric McCormack), Grace (Debra Messing) and Jack (Sean Hayes) are upset when they discover they’ve been too preoccupied with the changes in their own lives: Will teaching law at Columbia, Grace running for president of the New York Interior Designers Society and Jack’s new relationship with Estefan (guest star Brian Jordan Alvarez) to even notice Karen (Megan Mullally) has not been seen in days -- ever since her husband found out about her affair with Malcolm (guest star Alec Baldwin).