Union Saint-Gilloise look to qualify for the Europa League group stage in the first leg against heavy underdogs Lugano.
Ludogorets look to create a shock against Ajax at home in Bulgaria in the first leg of the Europa League play-off round.
Dinamo Zagreb take a commanding 3-1 lead into the second leg of the Europa League play-off round against Sparta Praha.
Čukarički conceded three to Olympiacos in the first leg and have everything to do with a spot in the Europa League group stage up for grabs.
U.S defender Erik Palmer-Brown and Greek giants Panathinaikos start their European run with a tough test against 2022 UCL semifinalist Villarreal.
Historic Swiss side Servette looks to continue their recent resurgence with a European run, but face stiff competition against Czech giants Slavia Praha.