Col. Mackenzie, new owner of the Shiloh Ranch, becomes embroiled in a controversy with the cattlemen's association when he insists on investigating the hanging of an accused cattle rustler; guest Don DeFore.
A Mexican girl's (Susana Miranda) indecision over whether to marry Trampas' friend (James Farentino) or her father's (Desi Arnaz) aide (Mario Alcade) threatens to touch off a gunfight between the two.
The Virginian rescues a woman (Janet Leigh) and renews an old friendship with her, only to discover she has been dishonest with him when outlaws attack the stage they are riding.
A captain's (Art Carney) plan to buy back his lost riverboat from lucky gambler Trampas falls into disarray when a train-robbery gang commandeers the vessel in question for a getaway; guest Tom Ewell.
A man Mackenzie rescues from a lynch mob becomes an unexpected hero when kidnappers (Robert Webber, Dane Clark) strike aboard the train they are all riding; guest Annette O'Toole.
Two brothers (Brandon de Wilde, John Smith) accuse the Virginian of being the man who widowed their mother (Agnes Moorehead), and a judge (Joseph Cotten) seems eager to agree with them.
