RB Leipzig kick off their pre-season tour of the United States against Aston Villa at the Red Bull Arena in New Jersey.
Alianza W take on Vancouver Whitecaps in a crucial clash in the Concacaf W Champions Cup preliminary round.
Alajuelense kick off Group A in the CONCACAF W Champions Cup against Frazsiers, who are looking to cause a stir after qualifying from Jamaica.
Santa Fe take on San Diego Wave in the opening match of Group B with both sides looking for a hot start in Panama City.
Club América kick off their group stage with eyes on all three points in Group B after a disappointing showing in the Summer Cup.
It's an all LIGA MX Femenil clash as Tigres UANL and Monterrey clash in Group A of the CONCACAF W Champions Cup.