Ruthless drug lord Pablo Escobar floods the United States with cocaine and terrorizes the nation of Colombia.
Joaquín Guzmán Loera AKA El Chapo is America's number one illegal drug supplier. After over a decade of searching, the DEA, Homeland Security and the US marshals combine forces with the Mexican marines to take him down.
In 1980 the trickle of cocaine coming in to Florida suddenly becomes a flood and drug wars erupt on the streets. Carlos Lehder is behind it all. The DEA must take him down before he destroys the USA with the drug he calls Latin America's atomic bomb.
In 1995 ruthless murderer and Boston crime boss James Whitey' Bulger flees Boston to escape an impending arrest. State police, the FBI and US Marshals all join an international hunt for this violent fugitive.
Frank Lucas was one of the most successful heroin dealers of the 1970's. His brand of heroin known as Blue Magic was notorious on the streets of New York and New Jersey.
The DEA are running an undercover mission codenamed Operation Relentless'. This is a multi-million dollar, international sting with one aim, to take down Russian arms dealer Viktor Bout also known as the Merchant of Death.