Chicago police begin a homicide investigation only to find themselves plunged into a world of savage crimes and occult rituals. Then, in a chapel in Toledo during Christianity's holiest season someone butchers a nun in a murder with satanic overtones.
In an Florida vacation spot a young woman has a horrifying encounter with a real-life vampire. Next, in a small, quiet town in New England, which is shaken when investigators suspect that a group of prostitutes is performing rituals to worship Satan.
A teenage boy arrives at a firehouse in Ohio with a terrifying message. Authorities rush to his house to find a grisly crime scene. Then, in Cleveland, a charming preacher gathers together a group of believers determined to bring on the end of the world.