The Reagans' professional lives converge when an allegation of jury tampering against Erin intertwines with Danny and Baez's homicide case and Eddie's bond to a child murder witness.
Danny gets involved when Sean becomes the latest victim in a series of robberies on Sean's college campus. Also, Erin grows suspicious of an overworked attorney who she believes isn't acting in his client's best interest.
Danny and Baez join forces with Danny's old partner, Jackie Curatola (Jennifer Esposito), when a serial killer reappears. Also, Eddie faces backlash when she tries to help a woman who accuses a sergeant of rape.
Frank grapples with the personal loss of his best friend and how best to help Tess Ross when she lands in jail. Jaime and his nephew, Joe Hill race against the clock to reunite a trafficking victim with her sister.
Erin's case against cartel member Carlos Munoz intersects with a husband-and-wife domestic abuse call that Jamie handled, but when the wife is murdered all hands are on deck, the husband becomes the prime suspect.