A journalist visits New Amsterdam to shadow Max (Ryan Eggold) and learn about the hospital. Bloom (Janet Montgomery) and Reynolds (Jocko Sims) have a major disagreement after she makes a call against protocol and Kapoor (Anupam Kher) deals with issues from his past.
The team must protect an ex-CIA agent to take down a cartel kingpin, an assignment that puts all of their lives in danger.
In tracking down the origin of a deadly strain of tuberculosis threatening Americans, Agent Ryan Booth must go undercover and infiltrate a white supremacist organization.
A patient's treatment plan takes an unexpected turn when Max (Ryan Eggold) gets overly invested. Meanwhile, Reynolds (Jocko Sims) celebrates his birthday with some help from the hospital and Kapoor (Anupam Kher) grapples with a case that hits close to home.
Alex and McQuigg are assigned to protect a prince following the assassination of an emir – but the team soon realizes the killer is closer than they think.
