Susan Grace

When Henry (guest star Howard Hesseman) experiences a seizure but is not aware of it while it’s happening, House takes on the case. The team’s differential diagnosis points to a bacterial infection, but Henry suffers a heart attack before the treatment for his infection is able to work, prompting the need for a heart transplant. Racing to find a heart donor in time to treat Henry before the infection kills him, House finds an organ donor who’s been declared unfit due to a mysterious illness.

Paul stands in the way of Susan receiving a kidney transplant; Tom passes up a lucrative job to continue working with Carlos; Andrew's alcohol consumption increases, worrying Bree.

J.D.'s ne'er-do-well brother (Tom Cavanagh) hits it off with Elliot.

Frankie and Mike attempt to have a romantic date night at home by renting a movie. But every time they turn it on, they end up falling asleep and try desperately to get through the film over a series of nights. Meanwhile, Axl teams up with Brick to invent the next big thing, and the Heck Brothers Old-Timey Barbecue Sauce is born; and Sue is floored when she's asked to her senior prom by a hunky mall store greeter. But she has to figure out a way to get out of work early in order to attend.

Mark, Teddy, Callie and Arizona help Sloan deliver her baby; the doctors treat a crab boat captain who was stabbed with a giant shark hook.