Meredith and the team are focused on helping Owen's sister after her shocking return, and Amelia faces a conflict over a patient. Meanwhile, Bailey is forced to give Grey Sloan a facelift after the fire, and the doctors are introduced to a few new faces that spice things up around the hospital.
Harper Avery arrives at Grey Sloan, putting Bailey on edge. A familiar face from Meredith's past returns as a patient, and Amelia tries to manage a secret.
Meredith is seemingly distracted and struggles to stay focused, and Maggie finds herself the keeper of a big secret while Amelia and Owen try to figure out their relationship. Meanwhile, Jo and Alex's honeymoon doesn’t go exactly as planned.
A hacker compromises the hospital's computer system, causing monitors, phones, labs, and patient files to all go down. As technology fails them, Bailey attempts to keep the peace, but chaos erupts and the doctors are forced to get creative in their methods to treat the patients.
April is in charge of the new Grey Sloan Surgical Innovation Contest, and the doctors are eager to start their projects. Meanwhile, Catherine's old friend has a shocking idea for Catherine and Jackson, and Meredith treats a returning patient who inspires her project.
