Meredith is seemingly distracted and struggles to stay focused, and Maggie finds herself the keeper of a big secret while Amelia and Owen try to figure out their relationship. Meanwhile, Jo and Alex's honeymoon doesn’t go exactly as planned.
Richard recruits Meredith and Bailey to help him launch a new program; Addison's patient has complications from a procedure; Jo helps a woman who goes into premature labor.
Harper Avery arrives at Grey Sloan, putting Bailey on edge. A familiar face from Meredith's past returns as a patient, and Amelia tries to manage a secret.
Meredith and the team are focused on helping Owen's sister after her shocking return, and Amelia faces a conflict over a patient. Meanwhile, Bailey is forced to give Grey Sloan a facelift after the fire, and the doctors are introduced to a few new faces that spice things up around the hospital.
The doctors contend with a pandemic.
