As Rossi conducts a profiling course on his birthday, he receives a call from his serial killer nemesis, Tommy Yates (Adam Nelson), telling him the location of his latest victim.
When the sisters of a Miami sorority are knocked off one by one, the CSIs try to end the murder spree. Bo Derek guest stars as Joanna Toring, the owner of a horse stable where a murder has been committed.
A notorious international weapons dealer returns to the states; Eric must go undercover at a bank.