Sarah Knowlton

House and the team take on the case of a struggling artist (guest star Breckin Meyer) who has been painting bizarre portraits. His undiagnosed illness is distorting his perception, threatening to undermine his career, his relationships and everything else in his life. The team soon finds out that he hasn’t sold anything lately and is on three separate drug trials to pay the bills. House must unlock the puzzle of which drugs are causing which symptoms before it’s too late. Meanwhile, House continues to have private investigator Lucas Douglas (guest star Michael Weston) dig up dirt on everyone on his team, including Taub who is having trouble in his marriage.

Jeff (Patrick Warburton) accidentally injects himself with Audrey's (Megyn Price) hormones for her fertility treatments on the day that they are attending her new boss? party. Adam (Oliver Hudson) forgets that it is Jennifer?s (Bianca Kajlich) birthday but is saved when Jeff gives him tickets to a Ranger?s game that he cannot attend. Russell (David Spade) regrets taking Timmy (Adhir Kalyan) to the hockey game, when his allegiance to the opposing team gets out of control.

It's Thanksgiving Day, and everyone at Mode celebrates in their own special way. Betty is torn between work and home; Daniel attends his parents' brunch in hopes of seeing Sofia (guest star Salma Hayek); Marc and Amanda camp out at the Mode offices, and Wilhelmina attempts something she's never done before - cooking a turkey.