Tensions rise when Holmes and Watson are forced to partner with Gareth Lestrade, Sherlock's former Scotland Yard colleague, on a bombing investigation. Sean Pertwee guest stars as Gareth Lestrade.
Jamie gets Danny involved when he finds a homeless teen who claims his aunt was killed by her boyfriend. Meanwhile, Erin is angered when McCoy replaces her as the prosecutor on a case involving a corrections officer.
When Bull assists Jules Caffrey, a high-powered attorney on trial for his fiancée’s murder, he takes advantage of his client’s penchant for courtroom theatrics by letting him defend himself.
Jackie shows Dr. O'Hara a fake MRI to get an oxy prescription. Dr. O'Hara confronts Orthopedics and finds out that Jackie faked her MRI. Mrs. Akalitus rehires Eddie as the hospital pharmacist. Mrs. Akalitus and Jackie advise the wife of a patient to divorce him so that they can avoid going bankrupt and he can qualify for Medicaid. Dr. Cooper is distraught over the end of the "Face of All Saints" campaign and offers to pay for a new round of ad space. Sam invites Dr. Cooper to hang with his friends and his girlfriend after work. On Jackie's way home, she helps a businessman having a seizure and discovers baggies of prescription pills in his jacket — he's a white collar drug dealer. Jackie steals his stash from him while they wait for EMS.
When scholarship funds from a prestigious Manhattan prep school mysteriously disappear, Neal poses as a substitute teacher to help Peter and the FBI figure out where the money is really going.
