As Grissom and Sara close in on who framed Hodges, the CSI team investigates a lock room murder mystery at 30,000 feet, when a cargo plane lands autonomously at McCarran Airport and everyone on board has been killed.
While the group works together to cross the Mississippi River, a plot to steer the teens back home hits a snag. A member of the group must overcome past trauma to save the others from an approaching threat.
