Regi Davis

Frasier's vacation plans with Claire turn disastrous when Daphne, Niles and Martin show up at the same resort and Frasier starts dreaming about Lana.

With Gideon missing, and Hotch and Prentiss off the team, the BAU investigates one of its most difficult cases yet as the remaining agents track a serial killer in Milwaukee who abducts women in public places by using his son as bait.

Izzie continues helping to plan Derek and Meredith's wedding in spite of her cancer treatments; things don't go smoothly when Callie introduces Arizona to her father; Owen seeks out help for his post-traumatic stress disorder.

On Brennan and Booth’s first official day back at their respective positions at the Jeffersonian and the FBI, things get exciting when remains are found at a fish farm under suspicious conditions, prompting them to investigate. After it’s discovered that someone harvested several of the victim’s internal organs before he was dumped in the water, Angela tracks down the seller and buyer of the organs to try to uncover important details in the case. Meanwhile, Booth readjusts to his position back at the FBI and discovers Aubrey has taken over his old office; Hodgins pushes Angela to showcase her photography work; and Cam struggles with her decision to choose work over her relationship with Arastoo.

Mike and Carl's annual pilgrimage to the Chicago Cubs' Opening Day is interrupted when Molly comes along.