The BAU is called to Wisconsin in search of a serial killer, and the team looks for a connection among the victims for clues to the UnSub. Also, Kate has trouble dealing with her niece, Meg, when she begins acting out.
When David Hodges goes missing, the entire CSI team searches for any piece of evidence that can help locate him, clear his name and save the reputation of the entire crime lab.
Don looks toward his newly found religious beliefs to help him contend with a escaped criminal bent on revenge.
Detective Cooper tries to enlist help to end a deadly gang war.