Patti Vasquez

Truck and squad are called to aid in a massive all city response when an old, ill equipped factory turned live/work space quickly turns into a firestorm, trapping countless unsuspecting victims. The dire situation quickly turns personal when it is discovered that one of Chicago PD's own has a family member at the scene. With the rescued victims in need of serious medical attention, the doctors and nurses of Chicago Med are tested as the major influx of patients are brought through their doors. Meanwhile, in the aftermath, the building owner steps forward to cooperate with the ongoing investigation, but the situation takes a sudden and unexpected turn.

When the squad's rig breaks down in the field, Casey (Jesse Spencer) reunites with his old friend and colleague Jason Kannell (guest star Kamal Angelo Bolden) from Squad 6, whose crew gets assigned a temporary change of quarters until the rig issue is resolved. Dawson (Monica Raymund) and Brett (Kara Killmer) serve their time in retraining, both tackling the class in unique ways. Severide (Taylor Kinney) tries to remedy what is going on with Anna (Charlotte Sullivan) and finds support from unlikely sources. As Connie (DuShon Monique Brown) returns from her family engagement, the crew lays bets on how long her temporary replacement Marcy (guest star Mia Hulen) will last.

Dawson finds it hard to keep her emotions in check during an ambo run involving a pregnant teen. Elsewhere, the firehouse is called to the site of a building fire and Casey is forced to make a split-second decision when two victims are each in need of life-saving assistance. In the aftermath, Casey is left to deal with the repercussions. Meanwhile, Severide shares a bond with Anna, as she makes her recovery.

From the Magnificent Mile in Chicago, it's standup comedy with some of America's funniest moms and dads. Hosted by Bonnie McFarlane. Performances by: Patti Vasquez, Jill Tasei, Ben Roy