When the COVID-19 pandemic hits Seattle the Station 19 crew lean on each other for support; Andy tries to make sense of her mother's return; a group of teenagers unintentionally starts a wild fire.
DeLuca has a seemingly incurable patient and turns to a diagnostics genius for help; Bailey checks in on Joey, a foster kid that Ben brought into Grey Sloan; Amelia is getting the results of her paternity test.
Andy and Jack fight to save people who are trapped in a collapsing bowling alley; Ben confronts Sullivan about his drug problem; Maya's mother pays her a visit.
Andy and Sullivan find a way to stay connected; Ben confronts a tough loss; Jack and Inara grow closer; while off duty, the crew jumps into action to help a mother in distress, but their heroic efforts spark conflict with police officers.
Ben finally faces the health issues he has been putting off; Jack and Inara help their neighbor out of a trashy situation; Carina and Maya reevaluate their relationship.