The CDC team are forced to work together when another outbreak threatens to overwhelm the Abbey.
The trail of Cleopatra's sarcophagus leads Danny and Lexi to the Bermuda Triangle, where a contact of Shaw's offers assistance tracking down a smuggler's plane that vanished years earlier. Also, Gwen attracts unwanted attention when she investigates a suspicious money transfer.
As Hardwick helps Danny and Lexi try to outmaneuver the Brotherhood, Danny learns shocking revelations that shatter everything he thought he knew about his past.
A special client calls Eric and his team to New York to negotiate a casualty-free resolution during a bank heist. When the robbers refuse to negotiate, the team convinces a timid security guard to help. But the case takes a surprising turn as they discover the robbers have no plan to escape and find a conspiracy that reaches to the wealthy and powerful. Meanwhile, Maxine gets a troubling text.
After Hank Galliston's wife, Leila, finds a special antique clock at a flea market, she is abducted by an international terrorist; as the search for Leila progresses, Hank questions everything he ever believed in.