The CDC team are forced to work together when another outbreak threatens to overwhelm the Abbey.
The trail of Cleopatra's sarcophagus leads Danny and Lexi to the Bermuda Triangle, where a contact of Shaw's offers assistance tracking down a smuggler's plane that vanished years earlier. Also, Gwen attracts unwanted attention when she investigates a suspicious money transfer.
As Hardwick helps Danny and Lexi try to outmaneuver the Brotherhood, Danny learns shocking revelations that shatter everything he thought he knew about his past.
After Hank Galliston's wife, Leila, finds a special antique clock at a flea market, she is abducted by an international terrorist; as the search for Leila progresses, Hank questions everything he ever believed in.