When Death Row inmate Clarence (guest star LL Cool J) mysteriously and suddenly collapses after hallucinating, House jumps at the chance to take the case for its difficulty and because it’s "cool." Dr. Cameron refuses to treat the patient in protest and feels they should treat a cancer patient because she’s more deserving, raising the question: is one life more important than another?
Two undercover cops are killed when a gun buy goes bad, and the treachery goes deeper than gangs - a defense attorney with a very personal involvement in the case is held responsible for the deaths.
At Rikers, an inmate named Calvin takes Naz into his confidence as Freddy continues to make protection overtures. On the outside looking in, Stone plays detective and uncovers some important information about Andrea's troubled past. Alison and Helen discuss a possible plea deal for Naz as Chandra counsels the accused.
Chandra has an unsettling encounter with a person of interest. Naz enjoys the perks of his alliance with Freddy. Stone finds relief from his eczema, and follows an intriguing new lead. Helen and Chandra make their opening statements as Naz's trial begins.
Salim and Safar reach the breaking point as their son's case moves into the defense phase. Stone eyes a link to Andrea's stepfather, a personal trainer partial to wealthy older women. Nearing retirement, Box is forced to return to the defense stand to explain a procedural blunder. Chandra summons a top forensic expert. Freddy loses a valuable pawn in Rikers.