Montse Hernandez

Jane (Gina Rodriguez) and Michael (Brett Dier) are back together and Jane wishes she had never left Michael in the first place. Rafael (Justin Baldoni) appears to have regressed to his playboy ways and Petra (Yael Grobglas) is concerned about him. But Petra is not aware that Rafael is helping Michael find Mutter's other son, Derek (guest star Mat Vairo). Rogelio's (Jaime Camil) new assistant, Paolo (guest star Ana De la Reguera), is actually his stalker Lola. Finally, Petra gives birth to the twins. Andrea Navedo and Ivonne Coll also star.

A shooting sends two of Drew's friends to the ER. Meanwhile, a woman's psychosis worsens, becoming a danger to herself and her father; Paul breaks hospital rules to treat a 9-year-old boy with severe cystic fibrosis; financial problems plague Ragosa.

TC's sister-in-law lands in the ER after falling down stairs, and complicated truths about the accident emerge. Meanwhile, staffers treat a boy who fell down a well; Ragosa's teen daughter visits the ER; and Drew spirals into a deeper depression.

In the season finale, after the Resistance kidnaps a high-value hostage, the Los Angeles bloc is placed on lockdown.