Monica Garcia

With his entire world changing around him, Sheldon is forced to confront an uncertain future and considers a major move in the seventh season finale. Meanwhile, Raj and Emily take it to the next level, and Mrs. Wolowitz's injury is a major headache for Howard and Bernadette. Recurring guest star CHRISTINE BARANSKI returns as Leonard's mother, Beverly Hofstadter.

Sheldon’s germophobia lands him in detention when flu season hits Medford and he takes extreme measures to remain healthy.

Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.

Lynette tries to talk her mother out of marrying an obnoxious man; Bree runs into Keith's ex-girlfriend and makes a shocking discovery about his past; Carlos starts to worry about Gaby's obsession.

When three restaurant workers are killed in a robbery/homicide in Las Vegas, N.M., the BAU looks at a cold case that happened in the town six years ago for leads.