Dr. Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join the prestigious St. Bonaventure hospital's surgical unit.
Eddie is determined to prove that he can still be a good father despite his physical challenges, and Sophie searches for answers to help cope with her trauma. Meanwhile, Rome and Tyrell work together on a passion project.
Sarah's respite in Iceland is ruined by a Neolution attack; when Sarah is forced to flee, she realizes she can never truly escape.
Sarah returns home to track down a new ally, following breadcrumbs to uncover the next facet of Neolution's agenda.
Sarah takes the day off to reconnect with Kira; Cosima infiltrates an exclusive Neolutionist fertility research center and makes a shocking discovery of their clandestine experiments.