The hospital has a pipe break which causes a huge flood; Meredith quits therapy but Dr. Wyatt doesn't believe she is finished.
The Seattle Grace staff continue to mourn George's death; Derek receives a proposition from the hospital board.
Jane gets the CBI involved in a case in Napa in order to focus on Sheriff McAllister, while Van Pelt and Rigsby finally take a trip down the aisle and get married.
The doctors form two teams to operate on conjoined twins; Bailey uses Meredith as a buffer between her and Ben; Alex learns a tough lesson; Teddy asks Cristina about Henry's surgery.
Sydney Bristow is a grad student by day, international spy by night. Her happiness over new engagment is shortlived as she learns some horrible truths about who she works for.