Michael Nathanson

Detective Sherlock Holmes, along with his sober companion, Dr. Joan Watson, uses his uncanny ability to read people and analyze crimes to assist the NYPD on some of their more difficult cases. In the season premiere, Holmes consults on a home invasion that resulted in murder.

Jack (Alec Baldwin) decides his commitment to Elisa (guest star Salma Hayek) is serious enough to go shopping for an engagement ring with Liz (Tina Fey). Tracy (Tracy Morgan), ironically, is the one Jack turns to for advice on how to deal with the pressures of married life. Meanwhile, Elisa divulges to Liz she is keeping a secret. When a prank results in an injury back at "TGS," Jenna (Jane Krakowski) loses her cool over an attractive EMT. Also stars Jack McBrayer, Judah Friedlander and Keith Powell.

Lockhart & Gardner leads a class action suit against a software company that allowed the Syrian government to "disappear" American citizens. Also, Will faces a hard decision in the wake of the Grand Jury proceedings. Guest Stars include Jonathan Groff, Rita Wilson, Parker Posey and Amy Sedaris.

Dr. Halstead (Nick Gehlfuss) and Sharon Goodwin (S. Epatha Merkerson) deal with a husband intent on harvesting his recently deceased wife's eggs, but soon discover some vital information that surprises everyone. Dr. Charles (Oliver Platt) is brought in by Dr. Choi (Brian Tee) to aid a patient who is trying to remove his own arm from his body because he feels like it doesn't belong. Nurse Sexton (Yaya DaCosta) befriends the father of a child who is rushed into the hospital after swallowing magnets - a situation that Dr. Rhodes (Colin Donnell) and Dr. Manning (Torrey DeVitto) are concerned could present dangerous complications. Meanwhile, Sarah Reese (Rachel DiPillo) finally learns about where she will do her residency, but has last-minute second thoughts.

A subway explosion leads to an influx of patients at The Knick, but little margin for profit. Pursued by Henry, Lucy takes to heart some advice given by one of Ping Wu's girls. An addict's misfortune gives Thackery an ideal test case for his latest theory on addiction. Bertie submits his adrenalin research to Zinberg; Cornelia gets a new clue in Speight's death; Barrow repays a debt but gets no credit; Genevieve charms the Chickerings; Harriet finds herself a boarding-house pariah.