Finch and Reese must delve into the murky waters of international politics when they are given the number of a former government contractor who is stalking a UN diplomat. Also, an enemy attempts to gain an upper hand on Root.
When Lawyer Elsbeth Tascioni is arrested putting a case she's working on in Jeopardy, Alicia, Will and Diane step up to aid the quirk Litigator. Meanwhile, Peter is presented with conflicting pieces of advice from Eli and Jordan. Carrie Preston, Maura Tierney and T.R. Knight guest star.
After a neighbor is stabbed, Dr. Choi (Brian Tee) enlists the help of April (Yaya DaCosta) to figure out who is the real cause of the incident. Dr. Bekker (Norma Kuhling) and Dr. Rhodes (Colin Donnell) expertise is put to the test when Noah (guest star Roland Buck III) misdiagnoses a patient. Dr. Charles (Oliver Platt) is put in an uncomfortable position when Dr. Reese's (Rachel DiPillo) estranged father (guest star Michel Gill) comes to him as a patient without her knowledge. Meanwhile, Dr. Manning (Torrey DeVitto) rushes to save a baby with whooping cough.
Upon hearing news of a pregnant teen, Dr. Manning (Torrey DeVitto) and Dr. Choi (Brian Tee) venture to a homeless encampment to help deliver a baby under dire circumstances. Dr. Rhodes (Colin Donnell) and Dr. Bekker (Norma Kuhling) argue about the best way to treat a young boy with a chronic disease. Dr. Halstead (Nick Gehlfuss) and April (Yaya DaCosta) are put in an uncomfortable situation when they find out their patient is a pedophile. Goodwin (S. Epatha Merkerson) and Maggie (Marlyne Barrett) have to deal with a lawsuit against the hospital. Dr. Charles (Oliver Platt) learns of important news pertaining to Dr. Reese's (Rachel DiPillo) father (guest star Michel Gill).
When a mother makes a decision regarding care of her vegetative adult son, Dr. Halstead and Dr. Manning find themselves at odds. Dr. Rhodes goes behind Dr. Bekker's back to figure out a way to get his patient at the top of the transplant list. Dr. Choi is at a loss when a woman in the waiting room falls asleep and won't wake up.