Mia Wesley

The neighbors are panicked about the intruder loose on Wisteria Lane, Susan learns shocking news about her father at her mother's wedding, Bree's "engagement" to George hits a bump, and Gabrielle learns to let go.

The doctors of Seattle Grace help Izzie cope with the loss of her fiancé, Denny, and her decision to quit the internship program. Meredith must decide what the future holds after her hospital liaison with Derek. The Chief is confronted by his wife, Adele, after spending the night in his office, and George seeks relationship advice from a surprising source, on the season premiere of "Grey's Anatomy."

Grissom and Warrick get the case of an old woman found mummified in her closet. Sara and Nick arrive to investigate a breaking and entering to find a raped teen.

Nate and Brenda discuss giving Maya a 'coherent narrative'; David and Keith await news from Mary, and meet a special little boy; Vanessa is shocked when Julio gets into trouble at school--and mortified when Rico schmoozes things over; Billy invites Claire to dinner, but has no appetite; Margaret helps stage an ambush; and Maggie brings George to a tense meal.

A man's gunshot-induced amnesia causes Jones and Medavoy to concoct an unconventional way to nail his assailant. A man Sipowicz put away twenty years ago for murdering a 12-year-old girl goes free. Ortiz and Ronson bust an underground pre-teen prostitution ring.