Mary Joy

As part of her Middle East peace-talks tour, President Meyer makes an historic trip to Iran, where an American reporter is being detained. Back in DC, Dan is wooed by lobbyist Sidney Purcell, while VP Doyle stands in for the President at a Rainbow Jersey event with a gay NBA star. Meanwhile, Kent's polling and Jonah's big mouth may cause trouble for Selina.

Addison takes temporary leave from Seattle Grace and makes a road trip to Los Angeles in order to visit some old friends from medical school. As Meredith continues to bond with her stepmother, Susan, Cristina reluctantly plans her wedding with the assistance of her mother, Helen, and Burke's mother, Mama Jane. Meanwhile, Derek must perform emergency surgery on Ava/Jane Doe, as Alex continues his unfailing bedside manner with her.

Addison gets a job offer away from Seattle Grace; Burke continues to have reservations about marrying Cristina; Susan returns to the hospital after feeling ill following the surgery.

Galavan and Penguin join forces with a dangerous family in Gotham. Then as the rivalry between the Waynes and the Galavans resurfaces Gordon struggles to maintain order in the city.

An overmedicated psychotic patient, James (Johnny Sneed), threatens Abby. Also, Abby learns news about her missing brother, Eric (recurring guest star Tom Everett Scott). Meanwhile, Romano continues to make rash judgments--and enemies--when he tries to perform a surgery in the emergency room. Kovac welcomes his longtime friend Gordana Horvat (Nina Sablich), a fellow Croatian doctor, who wants to observe the chaos of an inner-city American hospital. While Carter guides a group of eager medical students--who witness him tenaciously try to save a cardiac patient--he receives some emotional news from home.