Mark Hengst

Patrick Jane takes a personal interest in the case of a poisoned professor when the lead suspect is the victim’s wife – and Jane’s former pyschiatrist.

The team treats an underage and homeless female patient (guest star Bridgit Mendler), but when her symptoms worsen and call for an invasive surgery requiring adult consent, House and Adams argue over whether they should contact social services. The patient confesses that she ran away from home after struggling to take care of her mother, a recovering drug addict. But when her mother appears at her bedside, a more complicated relationship is revealed and the patient's mother must put the past aside and make the best decision for her daughter. Meanwhile, Taub has a difficult time connecting with his infant daughters and House threatens to exploit Foreman's relationship with a married woman (guest star Yaya DaCosta).

Members of Firehouse 51 are less than thrilled when Captain Patterson (guest star Brian White) steps in as replacement for Chief Boden (Eamonn Walker) while he deals with clearing his good name. When Severide (Taylor Kinney) learns of the potential whereabouts of Serena (guest star Ilfenesh Hadera), Chicago P.D's Officer Atwater (LaRoyce Hawkins) and Officer Ruzek (Patrick John Flueger) head to Lake Carlyle to try and uncover additional clues on Boden's case. Meanwhile, Herrmann (David Eigenberg) and Otis (Yuri Sardarov) give Freddie (guest star Ralph Rodriguez) a job that keeps him close by and Jimmy (Steven R. McQueen) and Chili (Dora Madison) elicit more attention then either bargained for, causing some friction between them.

The pressure on Firehouse 51 is at an all-time high as the internal affairs investigation into the handling of a recent fire picks up steam. Just when it appears that game-changing evidence comes to light that would serve to bail out Chief Boden (Eamonn Walker), new twists emerge that put his head right back on the chopping block. Brett (Kara Killmer) and Chili (Dora Madison) respond to a routine call and quickly find themselves in a life and death situation to help aid a stabbing victim who is bleeding out. Meanwhile, a stuck elevator summons the house to a high-rise hotel that tests everyone's mettle and candidate Jimmy Borrelli (guest star Steven R. McQueen) is conflicted when his older brother Danny (guest star Andy Ahrens) looks to get him transferred to a different house. Jesse Spencer, Taylor Kinney, Monica Raymund, David Eigenberg, Yuri Sardarov, Joe Minoso and Christian Stolte also star. Nick Gehlfuss, Oliver Platt, Brian Geraghty, Brian White, Rachel Nichols and Fredric Lehne also guest star.

Chief Boden (Eamonn Walker) confronts Maddox (guest star Mark Hengst), believing he is the hand behind Serena's (guest star Ilfenesh Hadera) accusations intended to skew Boden's credibility from the approaching trial. Severide (Taylor Kinney) reaches out to Jamie (guest star Rachel Nichols), Maddox's lawyer, in an effort to help out and Capt. Patterson (guest star Brian White) questions Boden's ability to remain Chief. Meanwhile, Brett (Kara Killmer) and Chili (Dora Madison) discover a man passed out in a garden that may have a connection to a call from a previous crash site and Otis looks to fill up his social calendar, but the situation hits a bump in the road.