Malina Weissman

In the series premiere episode, Superman's cousin, Kara Zor-El -- after 12 years of keeping her powers a secret on Earth -- decides to finally embrace her superhuman abilities and become the hero she was always meant to be.

When Kara's attempts to help National City don't go according to plan, she must put aside the doubts that she -- and the city's media -- has about her abilities in order to capture an escapee from the Kryptonian prison, Fort Rozz. Also, Cat pressures James to use his connection to Superman to get her an interview with Supergirl.

Kara's Thanksgiving may be ruined when she suspects her foster mother, Dr. Eliza Danvers (special guest star Helen Slater), who is coming to town, disapproves of her new role as a super hero. Also, when an accident transforms a volatile CatCo employee into the villainous Livewire, she targets Cat Grant and Supergirl. Brit Morgan guest stars as Leslie Willis/Livewire.

Kara goes toe-to-toe with Astra (recurring guest star Laura Benanti) when her aunt challenges Kara's beliefs about her mother. Also, Cat is threatened with being removed as the CEO of CatCo after a hacker exposes her private and damaging emails.

In the first season finale, Supergirl faces her greatest test yet when Non and Indigo plan to destroy every person on the planet -- forcing Kara to do battle with an unexpected foe and risk everything -- including her life.