A valuable Matisse painting is stolen from a museum. When the thief is found murdered, museum employee June Sinclair and her boyfriend David Lambert are charged with the crime.
Martin Selkirk is a major league rotter who wants Claire Allison in the worst way even though she's dating Dirk Benedict. Selkirk has Dirk's jaw broken and begins sending Claire threatening mail. Then Selkirk is murdered in his beach house and Claire is arrested for the crime. Perry takes the case and finds that the evidence points in the direction of Selkirk's five year old son. Or does it?
A brilliant young scientist is accused of his deceitful, greedy wife.
Perry Mason defends Della Street's socialite friend, Janet Brent, accused of murdering a blackmailer.
Jessica (Angela Lansbury) searches for the truth surrounding a 16-year-old murder case at the request of a dying Pulitzer Prize-winning author (Van Johnson). Guest stars: Efrem Zimbalist Jr., Bradford Dillman.