Holmes and Watson enter the world of nuclear security when they investigate the murder of an ex-Yakuza gang member. Also, Captain Gregson is blindsided by a stunning personal confession from his daughter, Hannah (Liza J. Bennett), a police sergeant.
Sookie hatches a dangerous plan to take down the H-Vamps, even as Vince and his armed vigilantes pose an equally serious threat. Lafayette gets high with James; Jason eyes a family future with Violet; Willa is forced to find a new place to stay; Sarah Newlin sheds her past. Pam offers Eric a compelling reason to return to Louisiana--and be the vampire he used to be.
Shortly after Frank awards a detective with the Medal of Valor for his undercover work for the NYPD in Malaysia, the detective is taken hostage by a Malaysian drug lord whose brother he helped put in prison. Meanwhile, Henry goes on a ride-along with Jaime and has a different method of getting the job done. Michelle Hurd guest stars.
The doctors contend with a pandemic.
Bailey finds herself in the middle of an argument with patients' families as they await news about their children who were injured in a fire; Winston surprises Maggie; Amelia and Link try to have some fun as new parents.