When a single human bone is discovered in the desert, Grissom and Catherine must cover miles of territory to find the rest of the skeleton.
Cory and Eric face different yet similar challenges - Cory is tempted by another girl, and Eric is tempted to settle for a mediocre college.
A former college professor, Roy Minard, asks Rush to reopen a murder case. Minard's career ended in disgrace when he became the prime suspect in the violent murder of his student Holly Rickter. Although Minard admits to a love affair with Holly, he maintains his innocence and hoping to finally clear his name and return to academia.
Sympathy and responsibility are at odds when Brenda volunteers for a teen crisis hotline. She violates the rules when she takes an after-hours call from a date-rape victim. Soon, Brenda is desperate to find her and help her.
While arranging to move into Connie's place, a frenzied Andy helps Clark Sr. escape from IAB's control. Meanwhile, Ortiz and McDowell work a shrink who may hold a clue to the death of a sexually voracious young woman; Tony's ex-wife picks up an old habit.