The BAU profiles a serial killer who takes families hostage and lives with them as a father figure during what is supposed to be their family vacations.
SSA David Rossi's personal and professional life is brought to the forefront when the BAU is called to investigate a case in Commack, Long Island, Agent Rossi's hometown.
Owen puts the residents through a rigorous trauma certification drill; Cristina is left alone to monitor an ill lung transplant patient.
Richard's 10,000th surgery is a liver transplant for two sisters; Derek and Lexie take on a case that had been declared inoperable; Teddy and Cristina try to swipe a case from Alex and Dr. McQueen; Meredith tries to choose a specialty.
When Sylvester accidentally triggers an explosive device during an investigation, Team Scorpion must focus on finding who's responsible even while their friend's life hangs in the balance.