When several women go missing in Virginia, the BAU must figure out what they have in common in order to find them.
The CBI team investigates the kidnapping of a couple (guest stars ANNE DUDEK and MICHAEL PETRONE) that may be the victim of mistaken identity, while Jane continues his investigation into Lorelei's whereabouts.
At the ranger station, Russell discovers a barely alive Air Force officer named Paxton (Nick Cokas) -- who's wearing a wet suit.
Russell must save Jesse after the teen is knocked unconscious by a mysterious, unknown force while checking out a submerged mobile home with Kira.
Underlay might get the quarantine he has requested when Russell discovers that escaped laboratory animals may be responsible for a deadly flu virus that has spread throughout Homestead.