Reese and Finch become trapped in a hospital which has just become ground zero for a deadly viral outbreak. Also, Samaritan’s newest recruit has second thoughts, and Shaw continues to struggle with reality.
Shaw escapes her captors, but the team is unsure of her mental state when she begins to act paranoid and reckless.
Root goes undercover at a radio station to protect the host of a conspiracy theory show who may have stumbled on information that someone is willing to kill to keep secret. Also, Samaritan’s agents try to convince a member of the team that their goals are noble.
Bull and Benny mount a difficult federal trial defense for a young mother accused of aiding and abetting her extremist husband in an act of domestic terrorism. When the controversial case makes news, Benny's commitment to TAC complicates his burgeoning political career.
In the series finale, everyone's story reaches a surprising yet inevitable conclusion.