Hank must confront his own worsening medical condition while treating the girlfriend of a HankMed regular. Also, Hank and Evan's cousin Owen arrives with a secret that throws the groom-to-be into a tail spin.
While HankMed treats a high-strung student for a bad case of nerves, her easy-going romance novelist mother falls ill as well and Hank must race to diagnose the two seemingly unconnected conditions.
Hank goes to Manhattan with Olympia, but their time away together isn't exactly what he expected. Evan fears Boris is keeping a secret from him within the hospital, and a surprise visitor from her past leads Divya to feel overwhelmed by the men in her life. Paige is eager for her home renovations to be finished and is shocked when she discovers the reason for the delay.
It's the holidays in the Hamptons! But an impending blizzard may derail Evan and Paige's wedding plans. Also, someone takes a big gamble on the future and a face from Hank's past triggers memories for Hank and Evan.
When a famous pop star comes to the Hamptons to prepare for her new world tour, HankMed must stay on hand to treat her for more than just exhaustion. Meanwhile, Divya becomes distracted when she falls head over heels for a globe-trotting polo player.