As Bull prepares for fatherhood, his work at TAC suffers without his top attorney, Benny, who quit in reaction to Bull's romantic reconnection to his ex-wife and Benny's sister, Isabella (Yara Martinez). In addition, the team faces a difficult time in court as they mount a defense for a young bartender on trial for involuntary manslaughter.
In the Season Two premiere, Max works to find a new normal three months after the catastrophic accident and the birth of his daughter. Kapoor grapples with the stigmas of aging, and Iggy has a successful day that inspires a life-changing idea. Meanwhile, Reynolds deals with an unreliable new intern.
Max and Sharpe wake up to a new, more personal dynamic. Iggy calls upon an old contact to help with an explosive situation at the hospital. Bloom begins a tricky dynamic with her new Emergency Department residents. Reynolds finds himself in an awkward position with Dr. Baptiste and his wife, Dr. Lyn Malvo.
It’s National HIV Testing Day and Max has offered free care to all HIV+ patients who come to New Amsterdam. Bloom and Reynolds butt heads over their opposing bedside manners. Iggy eagerly awaits the return of a friend. Sharpe discovers that she may need more hands on with her niece.
With the hospital on lockdown after the patients from Rikers escape from their beds, Helen and Max find themselves in a situation that could cost them their lives. Meanwhile, Bloom must put aside her pain to help a patient in need, and Iggy is forced to come to terms with the issues in his marriage.