Kathleen Bailey

Meredith grows increasingly dissatisfied with the unknown details of Derek's life. Meanwhile, Alex treats Devo, a patient whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her estranged mother; Zoey, a pregnant woman in her 40s who's been diagnosed with cancer, disagrees with Cristina's medical advice; and the interns are mystified by Cable, a patient who's being treated for seizures and who thinks he's psychic.

The residents of Wisteria Lane celebrate their annual holiday block party. Meanwhile, Gabrielle sets her eyes on a father of a girl she's coaching. Mike is arrested for Monique's murder. Thanks to Lynette, mothers of the neighborhood arrange a protest against Art. This causes his sister a heart attack. And Susan has to cook dinner for Ian's parents.

The Feds make a lot of promises in exchange for testimony, not all of them moral, and it's the Marshals who are stuck with the consequences. When art dealer Jay Arnstein goes into the witness protection program, he asks that his wife, Marci, be moved with him, as well as his mistress, Kay. The rules force Mary to keep this from Marci, a very sweet woman with whom she has an immediate bond. Things might have gone on like that forever, but when Jay is shot late one night at the gallery, everyone's secrets are forced out into the open.

After Mitch falls ill after swimming over contaminated waters, Cody, Caroline and CJ investigate the cause.