Mysteries unfold as Amy heads to Seattle on business and vanishes; Jack goes to Seattle only to uncover more unanswered questions about Amy's whereabouts; an old friend visits Jack and asks for his help. Meanwhile, nine-year-old Madison starts behaving erratically after seeing a stranger on the beach.
After a hunt gone wrong leaves Maggie’s whereabouts unknown, Sam, Dean, Mary and Bobby (recurring guest star JIM BEAVER) race to find her. But what they find are their own worst nightmares.