The life of a Reagan is put in danger when three dangerous criminals are released from prison.
The teenage son of a former friend hires her to defend him in a murder case, Alicia makes a difficult journey back to her old life.
The identical twin sister of a teenage girl requests Melinda to help her apologize to her sister who is a psychiatric patient.
When the team treats a 6-year-old with multiple health issues, they must collaborate with her mother (Jessica Collins), who is also a doctor; Wilson and House go on vacation.
While the FBI refocuses their efforts to catch “The Man in the Suit,” Reese’s latest POI becomes a personal quest after he learns that she’s the sister of a soldier who was killed in action.