When an inmate comes in with an entirely preventable illness, Max, Sharpe, and Iggy head directly to the source - Rikers Island. Meanwhile, Bloom struggles with her recovery, and Reynolds gets news that could change his life.
Max and Sharpe wake up to a new, more personal dynamic. Iggy calls upon an old contact to help with an explosive situation at the hospital. Bloom begins a tricky dynamic with her new Emergency Department residents. Reynolds finds himself in an awkward position with Dr. Baptiste and his wife, Dr. Lyn Malvo.
New Amsterdam is still reeling from the pandemic as a plane crash lands in the East River. When investigators come to interrogate the flight crew, Iggy fights against the clock to help the pilot uncover the truth. Max tracks down scarce medication after one of his own contracts COVID.
Max discovers a revenue-generating department at the hospital that has serious legal implications. Iggy discovers a janitor with otherworldly talents. Reynolds treats a truly inspirational patient and makes plans for his father. Wilder’s young patient teaches her not to jump to conclusions in diagnosing.
When an elder care facilitate shuts down, New Amsterdam is forced to intake many new patients. Max struggles with his decision to head back to London. Reynolds takes his personal frustrations out on his department with near disastrous results. Iggy's work causes him to reflect on his marriage and personal life.
