House and his team go to extreme measures to diagnose a young boy so he can in turn save his dying older brother’s life. With Nick's immune system completely wiped out from chemotherapy, Wilson is extremely cautious about keeping him healthy before the transplant.
Morgan is arrested as a serial killer after he goes home to Chicago to visit his family. Because the detective making the arrest had used a profile provided by Gideon, the team travels to Chicago to help the local authorities find the real killer and exonerate Morgan.
Zack and Cody become very popular once the cool kids discover they live at the Tipton, and the hotel soon becomes "party central." But after things get out of hand, the boys learn who their true friends are.
Nick represents a drug addicted mother as she attempts to regain custody of her children.
The case of two high school students, one dead and one missing, lead the CSIs into the underbelly of streetcar racing and a tangled web of deadly competition. (TV-14)