Ingrid Sanai Buron

House’s ex-girlfriend Stacy Warner (guest star Sela Ward) returns - not to be with House, but to get his help for her ailing husband. While House decides whether or not to take the case, Cuddy instructs him to substitute for a sick professor and present a lecture to a class of medical students. As he weaves the stories of three patients (including guest star Carmen Electra) who all present with a similar symptom, House gives a lecture the students will never forget. In the end, they come out with a broader understanding of diagnostics and House’s team comes out with a greater understanding of him.

Just before mobster Joey Arnello spills the beans in federal court and enters witness protection, he collapses. Is he faking? A court order instructs House to find out - and fast. House and his team struggle to diagnose and cure Joey while Joey’s brother Bill tries to slow things down and keep Joey from testifying. Meanwhile, Cuddy struggles to convince Vogler (guest star Chi McBride) that House is an essential part of the hospital. With Joey mysteriously slipping in and out of a coma, and House’s job on the line, House makes an exception to his own policy and gets to know his patient.

House diagnoses an injured young woman unable to feel pain, as he and the team search to find the source of her condition.

House encounters a brain-damaged musical prodigy with inexplicable abilities while the team faces serious concerns about House’s own health.

Gabrielle decides to get back into the world of modeling, Lynette is suspicious of her new neighbor and Bree meets her antagonistic mother-in-law.