Fred Kronenberg

The team encounters a teenage boy who collapsed from severe pelvic pain after playing basketball. Tests reveal the boy has genetic mosaicism, or both male and female DNA, and the boy's parents inform House and the team that the boy is unaware of his condition. They consciously chose a gender for him when he was born and raised him accordingly, never telling him about his unique condition. However, when his condition worsens and his life is threatened, the parents wonder whether they made the right decision. Meanwhile, Cuddy and Wilson suspect something is wrong with House when he starts acting way too nicely. When they discover the shocking answer, they must face the prospect that House may be changed forever.

Meredith's dishonesty is revealed, leading to unexpected consequences for her and others; the new chief resident is chosen.

When Terry, the attractive felon, gets off the stagecoach in Four Corners, Buck immediately begins to flirt with her, only to discover that she's accompanied by her very precocious young daughter.

Sam has to let Meryl down easy after Russ' good friend Ralph, a legend in the airline industry, offers to help him on a new project. When the project ends up becoming a circus, Sam begs Meryl to take him back - but she's not one to forgive that easy.