When Lux gets suspended from school, Cate does her best to convince Principal Dugan to give Lux a second chance, but, unfortunately, her efforts may have made the situation considerably worse for Lux.
After a young, healthy, and hunky fireman dies suddenly at Hope Zion, Alex must take the stand at M&M (Morbidity and Mortality) Rounds to find out what went wrong and who is to blame. Meanwhile, Charlie deals with a nervous soon-to-be Nun and Joel has to decide if he can be the man that comes through for Sonja.
When Alex is forced to put a patient’s gender reassignment surgery on hold, she discovers a secret in his medical history that could save his surgery, but tear his life apart. Charlie deals with a patient who is healthy, sane – and convinced she is going to die at midnight. Meanwhile, Joel secretly helps Sonia deal with a patient of hers who’s been admitted to Hope Zion.
Eddie’s injuries put a strain on his marriage as he secretly continues to manage the pain from the accident. Meanwhile, Rome struggles with his movie and finds an ally in Shanice; and Maggie continues her journey in England as she and Jamie grow closer than ever.
Alex is surprised twice in one night - first when she realizes she's been tricked into a blind double date, and again when she has to rush her mystery man to the E.R. Meanwhile, Charlie works to help a soldier move past a traumatic experience, and Maggie discovers a patient has a contagious illness that could put her own pregnancy at risk.