As the LAPD undergoes a major realignment, Brenda's team investigates the murder of a young girl who was house-sitting. Captain Raydor is forced to expand her audit of Major Crimes in light of the civil suit against Brenda and the LAPD.
The murder of two paramedics leads the LAPD and the FBI on separate investigations on a case that could be the precursor to a major terrorist attack. But Brenda fights to remain a step ahead, even though she's forced to work with the chief of the counterterrorism unit, who happens to be one of Brenda's fellow finalists for the job of Chief of Police.
Dre spirals when Rainbow is elected to the prestigious California Board of Medicine, and the invitation for the annual fundraising gala is addressed to Dr. Rainbow Johnson and guest; Diane redecorates her room to impress Mason.
Virtual interview guests include Los Angeles mayor Eric Garcetti, author Max Brooks, actor Seth MacFarlane, musician and activist Willie Nelson, and 2020 Democratic presidential candidate Senator Bernie Sanders.