When Sharpe has a case that hits close to home, she and Max team up to make things right for the patient. Meanwhile, Iggy and Bloom are forced to make a tough call on a unique situation.
Max journeys to Connecticut to bring Luna back to New York, but second-guesses his instincts when he sees her with her grandparents. Bloom takes action to ensure her staff feel safe at work while Reynolds takes a backseat in the cardiac unit. Sharpe struggles to lean on Dr. Cassian Shin (Daniel Dae Kim) while dealing with a family emergency.
Sharpe (Freema Agyeman) struggles when a case hits too close to home and Iggy (Tyler Labine) uncovers a patient's surprising past. Meanwhile, Floyd (Jocko Sims) makes progress in his personal life after some difficult news.
When a group of women on a retreat end up in the ED, Max gets some troubling information that could put a patient in jeopardy. Meanwhile, Sharpe and Kapoor work together to mend fences between two feuding sisters.
Max invokes a hospital-wide census in effort to get to know the staff of New Amsterdam on a deeper level. Reynolds takes a leap of faith that lands him in hot water, and Dr. Castro extends her treatment plan to more patients in the hospital.