In place of Ichimonji who heads to South America to pursue Doctor Reaper, Hongo once again comes to protect Japan.
Hongo's friend Sawada completes a liquid gunpowder that can melt any metal. The Shocker monster Poisonmondo targets this gunpowder.
Doctor Ootaguro succeeds in developing the “Alpha Liquid,” a life revitalizing drug that can revive a dead organism.
Doctor Reaper returns to Shocker's Japan branch of Katsugawa Island along with Catfishgiller who he remodeled from an electric catfish.
Shocker sets up a training camp in a village in the mountains. The monster Sea Snake Man who was trained at the camp uses the sight-warping Prism Eye to execute victims.