With Holmes facing criminal charges in the aftermath of his recent violent behavior and relapse, his powerful father Morland Holmes (John Noble) arrives in New York to fix his estranged son's troubles by any means necessary. Also, Holmes and Watson work the case of a missing wife believed to have been killed by her husband to try and get back in the NYPD's good graces.
When a debt collector is murdered, Holmes and Watson attempt to narrow down a suspect pool of thousands of consumers who owed the man money. Meanwhile, Watson's relationship with Andrew progresses when he asks her to meet his father for the first time.
Will helps a patient with long-haul Covid symptoms. Vanessa reflects on her dating life when she learns that a patient's daughter is having an arranged marriage. A new family is born out of tragedy.
